Exploration of biosynthetic access to the shared precursor of the fusicoccane diterpenoid family

Julia Arens; Benedikt Engels; Stephan Klopries; Stefan Jennewein; Christian Ottmann; Frank Schulz

doi:10.1039/C2CC37154E

Exploration of biosynthetic access to the shared precursor of the fusicoccane diterpenoid family†‡

Julia Arens,^ab Benedikt Engels,^c Stephan Klopries,^a Stefan Jennewein,^c Christian Ottmann^d and Frank Schulz*^ab

* Corresponding authors

^a Technische Universität Dortmund, Otto-Hahn-Straße 6, 44227 Dortmund, Germany
E-mail: frank3.schulz@tu-dortmund.de
Fax: +49 231 133-2498
Tel: +49 231 133-2429

^b Max Planck Institut für molekulare Physiologie, Otto-Hahn-Straße 11, 44227 Dortmund, Germany

^c Fraunhofer-Institut für Molekularbiologie und angewandte Ökologie, Forckenbeckstraße 6, 52074 Aachen, Germany

^d Chemical Genomics Centre, Otto-Hahn-Straße 15, 44227 Dortmund, Germany

Abstract

Herein preparative scale access to the shared precursor of the fusicoccane family of diterpenoids through biosynthesis in three different microbial hosts is reported. A method to purify the metabolite in high purity and on a preparative scale was explored.

This article is part of the themed collection: Emerging Investigators 2013

Supplementary files

Publication details

The article was received on 01 Oct 2012, accepted on 17 Dec 2012 and first published on 07 Jan 2013

Article type: Communication

DOI: 10.1039/C2CC37154E

Citation: Chem. Commun., 2013,49, 4337-4339

Request permissions
Exploration of biosynthetic access to the shared precursor of the fusicoccane diterpenoid family

J. Arens, B. Engels, S. Klopries, S. Jennewein, C. Ottmann and F. Schulz, Chem. Commun., 2013, 49, 4337
DOI: 10.1039/C2CC37154E
If you are not the author of this article and you wish to reproduce material from it in a third party non-RSC publication you must formally request permission using Copyright Clearance Center. Go to our Instructions for using Copyright Clearance Center page for details.

Authors contributing to RSC publications (journal articles, books or book chapters) do not need to formally request permission to reproduce material contained in this article provided that the correct acknowledgement is given with the reproduced material.

Reproduced material should be attributed as follows:
For reproduction of material from NJC:
Reproduced from Ref. XX with permission from the Centre National de la Recherche Scientifique (CNRS) and The Royal Society of Chemistry.

For reproduction of material from PCCP:
Reproduced from Ref. XX with permission from the PCCP Owner Societies.

For reproduction of material from PPS:
Reproduced from Ref. XX with permission from the European Society for Photobiology, the European Photochemistry Association, and The Royal Society of Chemistry.

For reproduction of material from all other RSC journals and books:
Reproduced from Ref. XX with permission from The Royal Society of Chemistry.
If the material has been adapted instead of reproduced from the original RSC publication "Reproduced from" can be substituted with "Adapted from".

In all cases the Ref. XX is the XXth reference in the list of references.

If you are the author of this article you do not need to formally request permission to reproduce figures, diagrams etc. contained in this article in third party publications or in a thesis or dissertation provided that the correct acknowledgement is given with the reproduced material.

Reproduced material should be attributed as follows:
For reproduction of material from NJC:
[Original citation] - Reproduced by permission of The Royal Society of Chemistry (RSC) on behalf of the Centre National de la Recherche Scientifique (CNRS) and the RSC

For reproduction of material from PCCP:
[Original citation] - Reproduced by permission of the PCCP Owner Societies

For reproduction of material from PPS:
[Original citation] - Reproduced by permission of The Royal Society of Chemistry (RSC) on behalf of the European Society for Photobiology, the European Photochemistry Association, and RSC

For reproduction of material from all other RSC journals:
[Original citation] - Reproduced by permission of The Royal Society of Chemistry
If you are the author of this article you still need to obtain permission to reproduce the whole article in a third party publication with the exception of reproduction of the whole article in a thesis or dissertation.

Information about reproducing material from RSC articles with different licences is available on our Permission Requests page.

Chemical Communications

Exploration of biosynthetic access to the shared precursor of the fusicoccane diterpenoid family†‡

Abstract

Supplementary files

Publication details

Exploration of biosynthetic access to the shared precursor of the fusicoccane diterpenoid family

Search articles by author

Spotlight

Advertisements