Issue 39, 2013
From the journal:

Chemical Communications

A multimodal, β-amyloid-targeted contrast agent†‡

Sashiprabha M. Vithanarachchia  and  Matthew J. Allen*a  

* Corresponding authors

a Department of Chemistry, Wayne State University, 5101 Cass Avenue, Detroit, USA
E-mail: mallen@chem.wayne.edu
Fax: +1 313 577 8822
Tel: +1 313 577 2070

Abstract

A multimodal, β-amyloid-targeted contrast agent was synthesized and studied in vitro. The agent has a higher relaxivity than a clinically approved contrast agent and interacts with β-amyloid aggregates producing changes in relaxation rate and fluorescence emission.

Graphical abstract: A multimodal, β-amyloid-targeted contrast agent

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Article information

DOI
https://doi.org/10.1039/C2CC36583A
Article type
Communication
Submitted
11 Sep 2012
Accepted
18 Oct 2012
First published
09 Nov 2012

Chem. Commun., 2013,49, 4148-4150

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A multimodal, β-amyloid-targeted contrast agent

S. M. Vithanarachchi and M. J. Allen, Chem. Commun., 2013, 49, 4148 DOI: 10.1039/C2CC36583A

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