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Issue 1, 2013
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A CO2-switchable polymer brush for reversible capture and release of proteins

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Abstract

We report on a polymer brush that can be switched between extended (hydrated) and collapsed (dehydrated) chain conformational states just by passing CO2 and an inert gas like N2 in solution alternately. This conformational change allows for reversible adsorption and release of a protein. In contrast to adding acids and bases for pH change, using gases as the trigger makes it possible to repeat the switching cycle many times without salt accumulation.

Graphical abstract: A CO2-switchable polymer brush for reversible capture and release of proteins

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Article information


Submitted
29 Aug 2012
Accepted
08 Nov 2012
First published
09 Nov 2012

Chem. Commun., 2013,49, 90-92
Article type
Communication

A CO2-switchable polymer brush for reversible capture and release of proteins

S. Kumar, X. Tong, Y. L. Dory, M. Lepage and Y. Zhao, Chem. Commun., 2013, 49, 90
DOI: 10.1039/C2CC36284H

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