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Issue 2, 2013
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Bio-ink for on-demand printing of living cells

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Abstract

Drop-on-demand bioprinting allows the controlled placement of living cells, and will benefit research in the fields of tissue engineering, drug screening and toxicology. We show that a bio-ink based on a novel microgel suspension in a surfactant-containing tissue culture medium can be used to reproducibly print several different cell types, from two different commercially available drop-on-demand printing systems, over long printing periods. The bio-ink maintains a stable cell suspension, preventing the settling and aggregation of cells that usually impedes cell printing, whilst meeting the stringent fluid property requirements needed to enable printing even from many-nozzle commercial inkjet print heads. This innovation in printing technology may pave the way for the biofabrication of multi-cellular structures and functional tissue.

Graphical abstract: Bio-ink for on-demand printing of living cells

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Article information


Submitted
09 Aug 2012
Accepted
11 Oct 2012
First published
05 Nov 2012

Biomater. Sci., 2013,1, 224-230
Article type
Paper

Bio-ink for on-demand printing of living cells

C. J. Ferris, K. J. Gilmore, S. Beirne, D. McCallum, G. G. Wallace and M. in het Panhuis, Biomater. Sci., 2013, 1, 224
DOI: 10.1039/C2BM00114D

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