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Issue 2, 2013
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Screening of cosmetic ingredients from authentic formulations and environmental samples with desorption electrospray ionization mass spectrometry

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Abstract

A rapid and sensitive method based on desorption electrospray ionization mass spectrometry (DESI-MS) has been utilized for the detection of chemicals related to cosmetic products without prior preparation. DESI-MS was used to rapidly screen target compounds at ambient conditions, allowing the investigation of surface-bound residues, complex chemical matrices, and components of authentic cosmetic formulations. This high-throughput method routinely achieved low nanogram detection limits, and quantitative ability was demonstrated with decent linearity and precision. Continuous, direct analysis of cosmetic impurities in drinking water matrices was also validated, implementing thermal assistance into the ionization source design to increase overall sensitivity.

Graphical abstract: Screening of cosmetic ingredients from authentic formulations and environmental samples with desorption electrospray ionization mass spectrometry

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Publication details

The article was received on 02 Aug 2012, accepted on 17 Nov 2012 and first published on 28 Nov 2012


Article type: Paper
DOI: 10.1039/C2AY25846C
Anal. Methods, 2013,5, 394-401

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    Screening of cosmetic ingredients from authentic formulations and environmental samples with desorption electrospray ionization mass spectrometry

    J. L. Nizzia, A. E. O'Leary, A. T. Ton and C. C. Mulligan, Anal. Methods, 2013, 5, 394
    DOI: 10.1039/C2AY25846C

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