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Issue 42, 2013
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Reversing the course of the competitive adsorption between a phospholipid and albumin at an air–water interface

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Abstract

When bovine serum albumin (BSA) and dipalmitoylphosphatidylcholine (DPPC) compete for occupation of an air–water interface, the protein rapidly colonizes the interface, effectively hindering the access of the phospholipid, a situation encountered in certain pulmonary conditions. We found that DPPC can totally and irreversibly displace BSA from the surface of a gas bubble when submitted to sustained sinusoidal oscillations at frequencies in the range of those encountered in respiration, and this without recourse to any additive.

Graphical abstract: Reversing the course of the competitive adsorption between a phospholipid and albumin at an air–water interface

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Article information


Submitted
16 Jul 2013
Accepted
21 Aug 2013
First published
21 Aug 2013

Soft Matter, 2013,9, 9972-9976
Article type
Communication

Reversing the course of the competitive adsorption between a phospholipid and albumin at an air–water interface

P. N. Nguyen, G. Waton, T. Vandamme and M. P. Krafft, Soft Matter, 2013, 9, 9972
DOI: 10.1039/C3SM51941D

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