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Issue 37, 2013
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Multi-responsive physical gels formed by a biosynthetic asymmetric triblock proteinpolymer and a polyanion

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Abstract

We report the design, production and characterization of a biosynthetic asymmetric triblock copolymer which consists of one collagen-like and one cationic block spaced by a hydrophilic random coiled block. The polymer associates into micelles when a polyanion is added due to the electrostatic interaction between the cationic block and the polyanion. The collagen-like block self-assembles into thermo-responsive triple helices upon cooling. When both end blocks are induced to self-assemble, a physical gel is formed via thermo-responsive association of the charge-driven micelles. The self-assembly of both end blocks and the effects of salt and temperature thereon were characterized by light scattering and rheology.

Graphical abstract: Multi-responsive physical gels formed by a biosynthetic asymmetric triblock protein polymer and a polyanion

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Article information


Submitted
25 Jun 2013
Accepted
02 Aug 2013
First published
07 Aug 2013

Soft Matter, 2013,9, 8923-8930
Article type
Paper

Multi-responsive physical gels formed by a biosynthetic asymmetric triblock protein polymer and a polyanion

T. T. H. Pham, J. Wang, M. W. T. Werten, F. Snijkers, F. A. de Wolf, M. A. Cohen Stuart and J. van der Gucht, Soft Matter, 2013, 9, 8923
DOI: 10.1039/C3SM51751A

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