Issue 44, 2013
From the journal:

RSC Advances

Microwave assisted extraction of betulin from birch outer bark†

Rui Ferreira,‡a   Helga Garcia,‡a   Andreia F. Sousa,bc   Carmen S. R. Freire,b   Armando J. D. Silvestre,b   Werner Kunz,d   Luís Paulo N. Rebeloa  and  Cristina Silva Pereira*a  

* Corresponding authors

a Instituto de Tecnologia Química e Biológica, Universidade Nova de Lisboa, Apartado 127, Oeiras, Portugal
E-mail: spereira@itqb.unl.pt
Web: http://www.itqb.unl.pt

b CICECO and Department of Chemistry, University of Aveiro, Campus de Santiago, 3810-193 Aveiro, Portugal

c Department of Chemical Engineering, University of Coimbra, Pólo II, Pinhal de Marrocos, 3030-290 Coimbra, Portugal

d Institute of Physical and Theoretical Chemistry, University of Regensburg, D-93040 Regensburg, Germany

Abstract

In this communication, we report a new method for the isolation of betulin, a triterpenoid with interesting pharmacological activities, from birch outer bark. Remarkably high purity betulin raw extracts were obtained, ca. 95 wt%, through microwave assisted extraction with limonene. This saves time and energy when compared to the conventional methods.

Graphical abstract: Microwave assisted extraction of betulin from birch outer bark

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Article information

DOI
https://doi.org/10.1039/C3RA43868F
Article type
Communication
Submitted
24 Jul 2013
Accepted
09 Sep 2013
First published
11 Sep 2013

RSC Adv., 2013,3, 21285-21288

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Microwave assisted extraction of betulin from birch outer bark

R. Ferreira, H. Garcia, A. F. Sousa, C. S. R. Freire, A. J. D. Silvestre, W. Kunz, L. P. N. Rebelo and C. Silva Pereira, RSC Adv., 2013, 3, 21285 DOI: 10.1039/C3RA43868F

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