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Issue 36, 2013
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A novel multicomponent microwave-assisted synthesis of 5-aza-adenines

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Abstract

A novel multicomponent strategy for the efficient synthesis of 5-aza-adenines was developed. 5-Aza-adenines were prepared in a one-pot fashion from 5-amino-1,2,4-triazoles, cyanamide and triethyl orthoformate under microwave irradiation. The operational simplicity, efficiency and accessibility of this method make it highly attractive for the generation of bioactive compound libraries.

Graphical abstract: A novel multicomponent microwave-assisted synthesis of 5-aza-adenines

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Publication details

The article was received on 19 Apr 2013, accepted on 21 Jun 2013 and first published on 28 Jun 2013


Article type: Paper
DOI: 10.1039/C3RA41932K
RSC Adv., 2013,3, 15850-15855

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    A novel multicomponent microwave-assisted synthesis of 5-aza-adenines

    A. V. Dolzhenko, S. A. Kalinina and D. V. Kalinin, RSC Adv., 2013, 3, 15850
    DOI: 10.1039/C3RA41932K

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