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Issue 18, 2013
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Accommodating fluorinated amino acids in a helical peptide environment

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Abstract

Fluorinated amino acids represent useful building blocks for structural and functional upgrading of peptides and proteins. Here, we report the identification of a suitable environment for fluorinated aminobutyric acids in a central d-position of a heterodimeric coiled-coil assembly via phage display.

Graphical abstract: Accommodating fluorinated amino acids in a helical peptide environment

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Publication details

The article was received on 05 Nov 2012, accepted on 07 Mar 2013 and first published on 14 Mar 2013


Article type: Communication
DOI: 10.1039/C3RA41110A
Citation: RSC Adv., 2013,3, 6319-6322
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    Accommodating fluorinated amino acids in a helical peptide environment

    E. K. Nyakatura, O. Reimann, T. Vagt, M. Salwiczek and B. Koksch, RSC Adv., 2013, 3, 6319
    DOI: 10.1039/C3RA41110A

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