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Issue 11, 2013
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Biodegradable polymer network encapsulated polyplex for DNA delivery

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Abstract

A novel gene delivery system is made by encapsulation of a polyplex between pDNA and cationic micelles with a biodegradable crosslinked shell. The outer shell can provide additional functionality to the system and protect DNA from degradation. The encapsulated polyplex exhibits a similar transfection efficiency compared to the naked polyplex.

Graphical abstract: Biodegradable polymer network encapsulated polyplex for DNA delivery

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Publication details

The article was received on 22 Aug 2012, accepted on 11 Jan 2013 and first published on 14 Jan 2013


Article type: Communication
DOI: 10.1039/C3RA21890B
RSC Adv., 2013,3, 3508-3511

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    Biodegradable polymer network encapsulated polyplex for DNA delivery

    P. D. Petrov, N. I. Ivanova, M. D. Apostolova and C. B. Tsvetanov, RSC Adv., 2013, 3, 3508
    DOI: 10.1039/C3RA21890B

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