Jump to main content
Jump to site search
Access to RSC content Close the message box

Continue to access RSC content when you are not at your institution. Follow our step-by-step guide.


Issue 27, 2013
Previous Article Next Article

Chemical approach for interconversion of (S)- and (R)-α-amino acids

Author affiliations

Abstract

Here we report a general method for the preparation of unnatural (R)-α-amino acids via complexation of α-(phenyl)ethylamine derived chiral reagent (S)-3 with various (S)-α-amino acids. The reactions proceed with synthetically useful chemical yields and thermodynamically controlled diastereoselectivity. Chiral reagent (S)-3 can be conveniently recovered and reused without any loss of enantiomeric purity and reactivity.

Graphical abstract: Chemical approach for interconversion of (S)- and (R)-α-amino acids

Back to tab navigation

Article information


Submitted
18 Mar 2013
Accepted
12 May 2013
First published
13 May 2013

Org. Biomol. Chem., 2013,11, 4503-4507
Article type
Paper

Chemical approach for interconversion of (S)- and (R)-α-amino acids

A. E. Sorochinsky, H. Ueki, J. L. Aceña, T. K. Ellis, H. Moriwaki, T. Sato and V. A. Soloshonok, Org. Biomol. Chem., 2013, 11, 4503
DOI: 10.1039/C3OB40541A

Social activity

Search articles by author

Spotlight

Advertisements