Jump to main content
Jump to site search

Issue 37, 2013
Previous Article Next Article

Pd(0)-catalyzed benzylic arylation–oxidation of 4-methylquinazolines via sp3 C–H activation under air conditions

Author affiliations

Abstract

An efficient and selective Pd(0)-catalyzed sp3 C–H bond arylation–oxidation of 4-methylquinazolines is reported. The method enables the introduction of arylketone at the benzylic position of 4-methylquinazolines without the use of an additional directing group, and atmospheric oxygen is used as the sole oxidant.

Graphical abstract: Pd(0)-catalyzed benzylic arylation–oxidation of 4-methylquinazolines via sp3 C–H activation under air conditions

Back to tab navigation

Supplementary files

Publication details

The article was received on 19 Jul 2013, accepted on 01 Aug 2013 and first published on 02 Aug 2013


Article type: Communication
DOI: 10.1039/C3OB41488D
Org. Biomol. Chem., 2013,11, 6246-6249

  •   Request permissions

    Pd(0)-catalyzed benzylic arylation–oxidation of 4-methylquinazolines via sp3 C–H activation under air conditions

    D. Zhao, M. Zhu, Y. Wang, Q. Shen and J. Li, Org. Biomol. Chem., 2013, 11, 6246
    DOI: 10.1039/C3OB41488D

Search articles by author

Spotlight

Advertisements