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Issue 5, 2013
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Synthesis and trypanocidal action of new adamantane substituted imidazolines

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Abstract

Introduction of the hydrophobic substituents cyclopentyl, cyclohexyl and phenyl into adamantane imidazolines was accomplished with the synthesis of compounds 4. Members of this series were found to display a range of activities against bloodstream forms of Trypanosoma brucei.

Graphical abstract: Synthesis and trypanocidal action of new adamantane substituted imidazolines

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Article information


Submitted
13 Mar 2013
Accepted
31 Mar 2013
First published
02 Apr 2013

Med. Chem. Commun., 2013,4, 856-859
Article type
Concise Article

Synthesis and trypanocidal action of new adamantane substituted imidazolines

A. Koperniku, I. Papanastasiou, G. B. Foscolos, A. Tsotinis, M. C. Taylor and J. M. Kelly, Med. Chem. Commun., 2013, 4, 856
DOI: 10.1039/C3MD00081H

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