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Issue 12, 2013
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Electrochemically-gated delivery of analyte bands in microfluidic devices using bipolar electrodes

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Abstract

A method for controlling enrichment, separation, and delivery of analytes into different secondary microchannels using simple microfluidic architecture is described. The approach, which is based on bipolar electrochemistry, requires only easily fabricated electrodes and a low-voltage DC power supply: no pumps or valves are necessary. Upon application of a voltage between two driving electrodes, passive bipolar electrodes (BPEs) are activated that result in formation of a local electric field gradient. This gradient leads to separation and enrichment of a pair of fluorescent analytes within a primary microfluidic channel. Subsequently, other passive BPEs can be activated to deliver the enriched tracers to separate secondary microchannels. The principles and performance underpinning the method are described.

Graphical abstract: Electrochemically-gated delivery of analyte bands in microfluidic devices using bipolar electrodes

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Publication details

The article was received on 09 Mar 2013, accepted on 17 Apr 2013 and first published on 08 May 2013


Article type: Paper
DOI: 10.1039/C3LC50321F
Lab Chip, 2013,13, 2292-2299

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    Electrochemically-gated delivery of analyte bands in microfluidic devices using bipolar electrodes

    K. Scida, E. Sheridan and R. M. Crooks, Lab Chip, 2013, 13, 2292
    DOI: 10.1039/C3LC50321F

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