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Issue 8, 2013
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Micro-optical lens array for fluorescence detection in droplet-based microfluidics

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Abstract

We demonstrate the design and integration of droplet-based microfluidic devices with microoptical element arrays for enhanced detection of fluorescent signals. We show that the integration of microlenses and mirror surfaces in these devices results in an 8-fold increase in the fluorescence signal and in improved spatial resolution. Using an array of microlenses, massively parallel detection of droplets containing fluorescent dyes was achieved, leading to detection throughputs of about 2000 droplets per second and per lens, parallelized over 625 measurement points.

Graphical abstract: Micro-optical lens array for fluorescence detection in droplet-based microfluidics

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Publication details

The article was received on 04 Dec 2012, accepted on 29 Jan 2013 and first published on 30 Jan 2013


Article type: Technical Innovation
DOI: 10.1039/C3LC41329B
Lab Chip, 2013,13, 1472-1475
  • Open access: Creative Commons BY license
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    Micro-optical lens array for fluorescence detection in droplet-based microfluidics

    J. Lim, P. Gruner, M. Konrad and J. Baret, Lab Chip, 2013, 13, 1472
    DOI: 10.1039/C3LC41329B

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