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Issue 18, 2013
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Cell pairing using a dielectrophoresis-based device with interdigitated array electrodes

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Abstract

We present a chip device with an array of 900 gourd-shaped microwells designed to pair single cells of different types. The device consists of interdigitated array (IDA) electrodes and uses positive dielectrophoresis to trap cells within the microwells. Each side of a microwell is on a different comb of the IDA, so that cells of different types are trapped on opposite sides of the microwells, leading to close cell pairing. Using this device, a large number of cell pairs can be formed easily and rapidly, making it a highly attractive tool for controllable cell pairing in a range of biological applications.

Graphical abstract: Cell pairing using a dielectrophoresis-based device with interdigitated array electrodes

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Publication details

The article was received on 07 May 2013, accepted on 02 Jul 2013 and first published on 03 Jul 2013


Article type: Communication
DOI: 10.1039/C3LC50561H
Lab Chip, 2013,13, 3650-3652

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    Cell pairing using a dielectrophoresis-based device with interdigitated array electrodes

    M. Şen, K. Ino, J. Ramón-Azcón, H. Shiku and T. Matsue, Lab Chip, 2013, 13, 3650
    DOI: 10.1039/C3LC50561H

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