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Issue 9, 2013
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Isotope ratio measurements in biological tissues using LA-ICP-MS – possibilities, limitations, and perspectives

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Abstract

This article describes the advantages and possibilities of using LA-ICP-MS for isotope ratio measurements, briefly comparing quadrupole, sector-field and multi-collector systems. It also discusses problems and limitations of the respective set-ups. A special focus lies on biological samples from stable isotope tracer experiments and on spatially resolved isotope ratio measurements including imaging of isotope ratios. The article explores if there are valid reasons why until now almost no one used LA-ICP-MS to image isotope ratios. It wants to encourage the ICP-MS community to realise the potential of using LA-ICP-MS for isotope ratio measurements in biological samples and to hopefully spur further developments and applications.

Graphical abstract: Isotope ratio measurements in biological tissues using LA-ICP-MS – possibilities, limitations, and perspectives

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Publication details

The article was received on 20 Feb 2013, accepted on 21 May 2013 and first published on 21 May 2013


Article type: Perspective
DOI: 10.1039/C3JA50058F
J. Anal. At. Spectrom., 2013,28, 1367-1371

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    Isotope ratio measurements in biological tissues using LA-ICP-MS – possibilities, limitations, and perspectives

    D. S. Urgast and J. Feldmann, J. Anal. At. Spectrom., 2013, 28, 1367
    DOI: 10.1039/C3JA50058F

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