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Issue 14, 2013
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A novel polynuclear Cu(i)–sulfur cluster with 1,2-dithiolate-o-carborane ligands as a potential in vitro antitumour agent and its DNA binding properties

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Abstract

A novel polynuclear Cu(I)–sulfur cluster, 1 (C54H62B30Cu6N8S6), bearing 1,2-dithiolate-o-carborane and 1,10-phenanthroline ligands was synthesized. The complex displayed rapid, low micromolar in vitro cytotoxicity against a range of epithelial tumour cells and efficient CT-DNA binding.

Graphical abstract: A novel polynuclear Cu(i)–sulfur cluster with 1,2-dithiolate-o-carborane ligands as a potential in vitro antitumour agent and its DNA binding properties

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Article information


Submitted
22 Dec 2012
Accepted
06 Feb 2013
First published
07 Feb 2013

Dalton Trans., 2013,42, 4777-4780
Article type
Communication

A novel polynuclear Cu(I)–sulfur cluster with 1,2-dithiolate-o-carborane ligands as a potential in vitro antitumour agent and its DNA binding properties

Z. Han, J. Jiang, J. Lu, D. Li, S. Cheng and J. Dou, Dalton Trans., 2013, 42, 4777
DOI: 10.1039/C3DT33076A

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