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Issue 38, 2013
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Metal-enhanced fluorescence in the life sciences: here, now and beyond

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Abstract

We discuss the phenomenon of enhanced fluorescence in the proximity of metal nanostructures addressing the question of how much fluorescence signal can be obtained from fluorophores in such altered environments. We review its applicability for the methodologies used in the life science, such as immunoassays, flow cytometry and bioimaging. Experimental and theoretical scenarios employing various metal nanostructures – such as homogeneous enhancing substrates, fluorescence-enhancing microbeads, and metal core–dielectric shell nanocomposites – are described.

Graphical abstract: Metal-enhanced fluorescence in the life sciences: here, now and beyond

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Publication details

The article was received on 17 Jan 2013, accepted on 22 Mar 2013 and first published on 22 Mar 2013


Article type: Perspective
DOI: 10.1039/C3CP50206F
Phys. Chem. Chem. Phys., 2013,15, 15695-15708

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    Metal-enhanced fluorescence in the life sciences: here, now and beyond

    W. Deng, F. Xie, H. T. M. C. M. Baltar and E. M. Goldys, Phys. Chem. Chem. Phys., 2013, 15, 15695
    DOI: 10.1039/C3CP50206F

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