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Issue 77, 2013
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Thiolated 2-methacryloyloxyethyl phosphorylcholine for an antifouling biosensor platform

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Abstract

We developed a new building block for a protein- and cell-repellant self-assembled monolayer (SAM) from 2-methacryloyloxyethyl phosphorylcholine (MPC) via a simple Michael-type addition to one mercapto group in alkanedithiol. The thiolated MPC can enable functionalization of a noble metal electrode to minimize noise signal in biosensing.

Graphical abstract: Thiolated 2-methacryloyloxyethyl phosphorylcholine for an antifouling biosensor platform

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Publication details

The article was received on 10 Jun 2013, accepted on 31 Jul 2013 and first published on 31 Jul 2013


Article type: Communication
DOI: 10.1039/C3CC44357D
Chem. Commun., 2013,49, 8683-8685

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    Thiolated 2-methacryloyloxyethyl phosphorylcholine for an antifouling biosensor platform

    T. Goda, M. Tabata, M. Sanjoh, M. Uchimura, Y. Iwasaki and Y. Miyahara, Chem. Commun., 2013, 49, 8683
    DOI: 10.1039/C3CC44357D

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