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Issue 68, 2013
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Detection of DNA induced gold nanoparticle aggregation with dark field imaging

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Abstract

Dark field imaging was employed to visualize and quantify complementary DNA-induced gold nanoparticle aggregation at the single-particle level, with a detection limit of 100 fM DNA, which allows the highly sensitive detection of single nucleotide polymorphisms (SNPs). Results suggested that the aggregation process is consistent with the cluster–cluster model.

Graphical abstract: Detection of DNA induced gold nanoparticle aggregation with dark field imaging

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The article was received on 04 Jun 2013, accepted on 27 Jun 2013 and first published on 28 Jun 2013


Article type: Communication
DOI: 10.1039/C3CC44182B
Chem. Commun., 2013,49, 7531-7533

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    Detection of DNA induced gold nanoparticle aggregation with dark field imaging

    T. Bu, T. Zako, M. Fujita and M. Maeda, Chem. Commun., 2013, 49, 7531
    DOI: 10.1039/C3CC44182B

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