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Issue 65, 2013
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A ratiometric fluorescent dye for the detection of glutathione in live cells and liver cancer tissue

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Abstract

A novel ratiometric biothiol probe Glutathione Green was developed. It allows quantitative measurement of glutathione in cell extracts and direct visualization of changes in glutathione levels in live cells. Remarkably, this is the first reported biothiol probe which can detect the carcinoma region of liver tissue based on the differences in the glutathione level.

Graphical abstract: A ratiometric fluorescent dye for the detection of glutathione in live cells and liver cancer tissue

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Article information


Submitted
10 May 2013
Accepted
19 Jun 2013
First published
19 Jun 2013

Chem. Commun., 2013,49, 7207-7209
Article type
Communication

A ratiometric fluorescent dye for the detection of glutathione in live cells and liver cancer tissue

D. Zhai, S. Lee, S. Yun and Y. Chang, Chem. Commun., 2013, 49, 7207
DOI: 10.1039/C3CC43480J

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