Issue 73, 2013

Crosstalk between Cu(i) and Zn(ii) homeostasis via Atx1 and cognate domains

Abstract

The copper metallochaperone Atx1 and the N-terminal metal-binding domain of a copper-transporting ATP-ase can form tight Zn(II)-mediated hetero-complexes in both cyanobacteria and humans. Copper and zinc homeostasis could be linked by metal binding to these CXXC-containing proteins.

Graphical abstract: Crosstalk between Cu(i) and Zn(ii) homeostasis via Atx1 and cognate domains

Supplementary files

Article information

Article type
Communication
Submitted
12 Apr 2013
Accepted
24 Jul 2013
First published
25 Jul 2013
This article is Open Access
Creative Commons BY license

Chem. Commun., 2013,49, 8000-8002

Crosstalk between Cu(I) and Zn(II) homeostasis via Atx1 and cognate domains

A. Badarau, A. Baslé, S. J. Firbank and C. Dennison, Chem. Commun., 2013, 49, 8000 DOI: 10.1039/C3CC42709A

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