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Issue 53, 2013
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Molecularly-imprinted nanoparticles that recognize Naja mossambica cytotoxins: binding studies and biological effects

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Abstract

We report the development of molecularly imprinted polyacrylamide nanoparticles that bind to and neutralize the activity of cytotoxins present in the venom of the Mozambique Spitting Cobra (Naja mossambica mossambica). The binding activity of these nanoparticles is avid and specific. These findings hold promise for the development of a synthetic antivenom.

Graphical abstract: Molecularly-imprinted nanoparticles that recognize Naja mossambica cytotoxins: binding studies and biological effects

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Article information


Submitted
02 Apr 2013
Accepted
21 May 2013
First published
28 May 2013

Chem. Commun., 2013,49, 5954-5956
Article type
Communication

Molecularly-imprinted nanoparticles that recognize Naja mossambica cytotoxins: binding studies and biological effects

S. Piszkiewicz, E. A. Kirkbride, N. Doreng-Stearns, B. R. Henderson, M. A. Lenker, E. Tang, L. H. Kawashiri, C. S. Nichols, S. C. Moore and S. G. Sogo, Chem. Commun., 2013, 49, 5954
DOI: 10.1039/C3CC42394H

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