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Issue 46, 2013
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Hyperpolarization of amino acid precursors to neurotransmitters with parahydrogen induced polarization

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Abstract

Several important neurotransmitter precursors were hyperpolarized via homogeneous hydrogenation with parahydrogen. Polarization enhancement was achieved for 1H and 13C spins by several orders of magnitude compared to thermal spectra. Such large signal enhancements of these molecules could facilitate neurotransmitter studies.

Graphical abstract: Hyperpolarization of amino acid precursors to neurotransmitters with parahydrogen induced polarization

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Article information


Submitted
17 Jan 2013
Accepted
21 Apr 2013
First published
23 Apr 2013

Chem. Commun., 2013,49, 5304-5306
Article type
Communication

Hyperpolarization of amino acid precursors to neurotransmitters with parahydrogen induced polarization

P. C. Soon, X. Xu, B. Zhang, F. Gruppi, J. W. Canary and A. Jerschow, Chem. Commun., 2013, 49, 5304
DOI: 10.1039/C3CC40426A

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