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Issue 17, 2013
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Single-molecule DNA detection using a novel SP1 protein nanopore

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Abstract

SP1 protein as a new type of biological nanopore is described and is utilized to distinguish single-stranded DNA at the single-molecule level. Using the SP1 nanopore to investigate single molecule detection broadens the existing research areas of pore-forming biomaterials from unsymmetrical biological nanopores to symmetrical biological nanopores. This novel nanopore could provide a good candidate for single-molecule detection and characterization of biomaterial applications.

Graphical abstract: Single-molecule DNA detection using a novel SP1 protein nanopore

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Article information


Submitted
14 Dec 2012
Accepted
10 Jan 2013
First published
11 Jan 2013

Chem. Commun., 2013,49, 1741-1743
Article type
Communication

Single-molecule DNA detection using a novel SP1 protein nanopore

H. Wang, Y. Li, L. Qin, A. Heyman, O. Shoseyov, I. Willner, Y. Long and H. Tian, Chem. Commun., 2013, 49, 1741
DOI: 10.1039/C3CC38939A

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