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Issue 99, 2013
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A new versatile approach to synthesise enantioenriched 3-hydroxyoxindoles, 1,3-dihydroisobenzofuran and 3-isochromanone derivatives by a rhodium-catalyzed asymmetric arylation–cyclization sequence

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Abstract

A novel arylation–cyclization strategy for the highly enantioselective synthesis of titled heterocycles with a quaternary stereogenic center has been developed.

Graphical abstract: A new versatile approach to synthesise enantioenriched 3-hydroxyoxindoles, 1,3-dihydroisobenzofuran and 3-isochromanone derivatives by a rhodium-catalyzed asymmetric arylation–cyclization sequence

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Publication details

The article was received on 15 Oct 2013, accepted on 19 Oct 2013 and first published on 22 Oct 2013


Article type: Communication
DOI: 10.1039/C3CC47927G
Chem. Commun., 2013,49, 11659-11661

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    A new versatile approach to synthesise enantioenriched 3-hydroxyoxindoles, 1,3-dihydroisobenzofuran and 3-isochromanone derivatives by a rhodium-catalyzed asymmetric arylation–cyclization sequence

    Y. Li, D. Zhu and M. Xu, Chem. Commun., 2013, 49, 11659
    DOI: 10.1039/C3CC47927G

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