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Issue 99, 2013
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A new versatile approach to synthesise enantioenriched 3-hydroxyoxindoles, 1,3-dihydroisobenzofuran and 3-isochromanone derivatives by a rhodium-catalyzed asymmetric arylation–cyclization sequence

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Abstract

A novel arylation–cyclization strategy for the highly enantioselective synthesis of titled heterocycles with a quaternary stereogenic center has been developed.

Graphical abstract: A new versatile approach to synthesise enantioenriched 3-hydroxyoxindoles, 1,3-dihydroisobenzofuran and 3-isochromanone derivatives by a rhodium-catalyzed asymmetric arylation–cyclization sequence

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Article information


Submitted
15 Oct 2013
Accepted
19 Oct 2013
First published
22 Oct 2013

Chem. Commun., 2013,49, 11659-11661
Article type
Communication

A new versatile approach to synthesise enantioenriched 3-hydroxyoxindoles, 1,3-dihydroisobenzofuran and 3-isochromanone derivatives by a rhodium-catalyzed asymmetric arylation–cyclization sequence

Y. Li, D. Zhu and M. Xu, Chem. Commun., 2013, 49, 11659
DOI: 10.1039/C3CC47927G

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