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Issue 47, 2013
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Enantioselective total synthesis of (+)-brazilin, (−)-brazilein and (+)-brazilide A

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An enantioselective strategy for the synthesis of (+)-brazilin, (−)-brazilein and (+)-brazilide A has been developed. A Lewis acid mediated lactonization established the novel fused bis-lactone core of brazilide A and finalized the first total synthesis of (+)-brazilide A.

Graphical abstract: Enantioselective total synthesis of (+)-brazilin, (−)-brazilein and (+)-brazilide A

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Publication details

The article was received on 02 Apr 2013, accepted on 23 Apr 2013 and first published on 09 May 2013

Article type: Communication
DOI: 10.1039/C3CC42385A
Chem. Commun., 2013,49, 5405-5407

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    Enantioselective total synthesis of (+)-brazilin, (−)-brazilein and (+)-brazilide A

    X. Wang, H. Zhang, X. Yang, J. Zhao and C. Pan, Chem. Commun., 2013, 49, 5405
    DOI: 10.1039/C3CC42385A

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