Jump to main content
Jump to site search
Access to RSC content Close the message box

Continue to access RSC content when you are not at your institution. Follow our step-by-step guide.


Issue 48, 2013
Previous Article Next Article

Asymmetric amplification in the catalytic enantioselective 1,2-addition of Grignard reagents to enones

Author affiliations

Abstract

Large asymmetric amplification originating from solubility differences between the enantiopure and the racemic catalyst is observed in the addition of Grignard reagents to enones. This behaviour is not reaction or catalyst specific and is observed for metal complexes of a variety of chiral diphosphine ligands, extensively used in asymmetric catalysis.

Graphical abstract: Asymmetric amplification in the catalytic enantioselective 1,2-addition of Grignard reagents to enones

Back to tab navigation

Supplementary files

Article information


Submitted
13 Mar 2013
Accepted
22 Apr 2013
First published
23 Apr 2013

Chem. Commun., 2013,49, 5450-5452
Article type
Communication

Asymmetric amplification in the catalytic enantioselective 1,2-addition of Grignard reagents to enones

F. Caprioli, A. V. R. Madduri, A. J. Minnaard and S. R. Harutyunyan, Chem. Commun., 2013, 49, 5450
DOI: 10.1039/C3CC41892H

Social activity

Search articles by author

Spotlight

Advertisements