Jump to main content
Jump to site search

Issue 19, 2013
Previous Article Next Article

Transfer of a protein pattern from self-assembled DNA origami to a functionalized substrate

Author affiliations

Abstract

Patterns of the protein streptavidin on DNA origami are printed onto a functionalized surface. The streptavidins are linked to DNA via a disulfide spacer and these conjugates self-organise into a predetermined pattern on DNA origami. The structure immobilises on a biotin-SAM-functionalized Au surface. By disulfide cleavage the origami is separated from the streptavidins, leaving the protein pattern at the surface.

Graphical abstract: Transfer of a protein pattern from self-assembled DNA origami to a functionalized substrate

Back to tab navigation

Supplementary files

Article information


Submitted
10 Oct 2012
Accepted
10 Jan 2013
First published
10 Jan 2013

Chem. Commun., 2013,49, 1927-1929
Article type
Communication

Transfer of a protein pattern from self-assembled DNA origami to a functionalized substrate

K. Busuttil, A. Rotaru, M. Dong, F. Besenbacher and K. V. Gothelf, Chem. Commun., 2013, 49, 1927
DOI: 10.1039/C3CC37408D

Social activity

Search articles by author

Spotlight

Advertisements