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Issue 12, 2013
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High specific phosphopeptides enrichment by titanium silicalite with post-treatment of desilication

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Abstract

The titanium silicalite-1 (TS-1) with post-treatment of chemical selective desilication (T-TS-1) has been synthesized, characterized and applied as a potential adsorbent for selective capture of phosphopeptides from complex biological samples prior to mass spectrometry analysis. A T-TS-1 material-based successive phosphopeptide enrichment strategy has also been established for real biological sample analysis, which exhibited high enrichment selectivity and is comparable to existing materials.

Graphical abstract: High specific phosphopeptides enrichment by titanium silicalite with post-treatment of desilication

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Publication details

The article was received on 11 Jan 2013, accepted on 21 Mar 2013 and first published on 22 Mar 2013


Article type: Communication
DOI: 10.1039/C3AY00064H
Anal. Methods, 2013,5, 2939-2946

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    High specific phosphopeptides enrichment by titanium silicalite with post-treatment of desilication

    B. Xu, C. Chen, F. Wang, Y. Bian, K. Cheng, H. Qin, C. Song, J. Zhu, J. Liu, M. Ye and H. Zou, Anal. Methods, 2013, 5, 2939
    DOI: 10.1039/C3AY00064H

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