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Issue 15, 2013
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Nano-particle modified stationary phases for high-performance liquid chromatography

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Abstract

This review covers the latest developments and applications of nano-materials in stationary phase development for various modes of high-performance liquid chromatography. Specific attention is placed upon the development of new composite phases, including the synthetic and immobilisation strategies used, to produce either encapsulated nano-particles, or surface attached nano-particles, layers, coatings and other structures. The resultant chromatographic applications, where applicable, are discussed with comment upon enhanced selectivity and/or efficiency of the nano-particle modified phases, where such effects have been identified. In the main this review covers developments over the past five years and is structured according to the nature of the nano-particles themselves, including carbonaceous, metallic, inorganic, and organopolymer based materials.

Graphical abstract: Nano-particle modified stationary phases for high-performance liquid chromatography

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Publication details

The article was received on 14 Mar 2013, accepted on 29 May 2013 and first published on 30 May 2013


Article type: Critical Review
DOI: 10.1039/C3AN00508A
Analyst, 2013,138, 4229-4254

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    Nano-particle modified stationary phases for high-performance liquid chromatography

    E. P. Nesterenko, P. N. Nesterenko, D. Connolly, X. He, P. Floris, E. Duffy and B. Paull, Analyst, 2013, 138, 4229
    DOI: 10.1039/C3AN00508A

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