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Issue 5, 2013
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Highly efficient ionization of phosphopeptides at low pH by desorption electrospray ionization mass spectrometry

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Abstract

A fast and novel strategy for efficient ionization of phosphopeptides in mixtures is reported, in which the sample is acidified to low pH to suppress the deprotonation of phosphate groups and then followed by direct analysis using liquid sample desorption electrospray ionization mass spectrometry (DESI-MS).

Graphical abstract: Highly efficient ionization of phosphopeptides at low pH by desorption electrospray ionization mass spectrometry

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Article information


Submitted
22 Nov 2012
Accepted
09 Jan 2013
First published
09 Jan 2013

Analyst, 2013,138, 1321-1324
Article type
Communication

Highly efficient ionization of phosphopeptides at low pH by desorption electrospray ionization mass spectrometry

N. Pan, P. Liu, W. Cui, B. Tang, J. Shi and H. Chen, Analyst, 2013, 138, 1321
DOI: 10.1039/C3AN36737A

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