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Issue 23, 2013
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Glucose selective Surface Plasmon Resonance-based bis-boronic acid sensor

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Abstract

Saccharides – a versatile class of biologically important molecules – are involved in a variety of physiological and pathological processes, but their detection and quantification is challenging. Herein, surface plasmon resonance and self-assembled monolayers on gold generated from bis-boronic acid bearing a thioctic acid moiety, whose intramolecular distance between the boronic acid moieties is well defined, are shown to detect D-glucose with high selectivity, demonstrating a higher affinity than other saccharides probed, namely D-galactose, D-fructose and D-mannose.

Graphical abstract: Glucose selective Surface Plasmon Resonance-based bis-boronic acid sensor

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Article information


Submitted
29 Apr 2013
Accepted
18 Sep 2013
First published
22 Oct 2013

This article is Open Access

Analyst, 2013,138, 7140-7145
Article type
Paper

Glucose selective Surface Plasmon Resonance-based bis-boronic acid sensor

A. Stephenson-Brown, H. Wang, P. Iqbal, J. A. Preece, Y. Long, J. S. Fossey, T. D. James and P. M. Mendes, Analyst, 2013, 138, 7140
DOI: 10.1039/C3AN01233F

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