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Issue 18, 2013
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Electroanalytical methodologies for the detection of S-nitrosothiols in biological fluids

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Abstract

The interest in the detection and quantification of S-nitrosothiols or thionitrites RSNOs in biological media and their use as pharmaceutical agents is mainly related to the discovery of nitric oxide as an endothelium relaxing factor, and analytical methodologies that are able to detect these moieties in real time, in situ and ideally with high sensitivity and selectivity could help in a better understanding of their biological pathways. In this review, we discuss the performances of the electroanalytical strategies developed for the sensing of low molecular weight RSNOs in biological fluids.

Graphical abstract: Electroanalytical methodologies for the detection of S-nitrosothiols in biological fluids

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Publication details

The article was received on 11 Mar 2013, accepted on 07 Jul 2013 and first published on 08 Jul 2013


Article type: Critical Review
DOI: 10.1039/C3AN00488K
Analyst, 2013,138, 5173-5181

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    Electroanalytical methodologies for the detection of S-nitrosothiols in biological fluids

    S. Griveau and F. Bedioui, Analyst, 2013, 138, 5173
    DOI: 10.1039/C3AN00488K

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