Jump to main content
Jump to site search

Issue 9, 2013
Previous Article Next Article

In-process phase growth measurement technique in the fabrication of monolithic porous layer open tubular (monoPLOT) columns using capacitively coupled contactless conductivity

Author affiliations

Abstract

A technique for the in-process measurement of polymer stationary phase growth inside fused silica capillaries during the fabrication of monolithic porous layer open tubular (monoPLOT) columns is presented. In this work, capacitively coupled contactless conductivity detection (C4D) was applied as an online measurement tool for porous polymer layer growth within fused silica capillaries. The relationship between effective capillary diameter and C4D response was investigated for two polymers, butyl methacrylateethylene dimethacrylate (BuMA–EDMA) and polystyrene–divinylbenzene (PS–DVB) over a range of capillary diameters and layer thicknesses. The described technique can be used with both thermal and photo-initiated approaches for monoPLOT fabrication and provides an accurate, real-time measurement of the porous layer growth within the capillary, which should vastly improve column-to-column reproducibility. The technique was shown to be very precise, with a measured %RSD < 10%.

Graphical abstract: In-process phase growth measurement technique in the fabrication of monolithic porous layer open tubular (monoPLOT) columns using capacitively coupled contactless conductivity

Back to tab navigation

Article information


Submitted
18 Jan 2013
Accepted
05 Feb 2013
First published
05 Feb 2013

Analyst, 2013,138, 2540-2545
Article type
Paper

In-process phase growth measurement technique in the fabrication of monolithic porous layer open tubular (monoPLOT) columns using capacitively coupled contactless conductivity

D. A. Collins, E. P. Nesterenko, D. Brabazon and B. Paull, Analyst, 2013, 138, 2540
DOI: 10.1039/C3AN00133D

Social activity

Search articles by author

Spotlight

Advertisements