Jump to main content
Jump to site search

Issue 5, 2013
Previous Article Next Article

Ion concentration polarization in a single and open microchannel induced by a surface-patterned perm-selective film

Author affiliations

Abstract

We describe a novel and simple mechanism for inducing ion concentration polarization (ICP) using a surface-patterned perm-selective nanoporous film like Nafion in single, open microchannels. Such a surface-patterned Nafion film can rapidly transport only cations from the anodic side to the cathodic side through the nanopore clusters so that it is possible to generate an ICP phenomenon near the Nafion film. In this work, we characterize transport phenomena and distributions of ion concentration under various electric fields near the Nafion film and show that single-channel based ICP (SC-ICP) is affected by Nafion film thicknesses, strengths of applied electric fields, and ionic strengths of buffer solutions. We also emphasize that SC-ICP devices have several advantages over previous dual-channel ICP (DC-ICP) devices: easy and simple fabrication processes, inherently leak-tight, simple experimental setup requiring only one pair of electrodes, stable and robust ICP induced rapidly, and low electrical resistances helping to avoid Joule heating, and membrane perm-selectivity breakdown but allowing as high bulk flow as an open, plain microchannel. As an example of applications, we demonstrate that SC-ICP devices not only have high potential in pre-concentrating proteins in massively parallel microchannels but also enable the concentration and lysis of bacterial cells simultaneously and continuously on a chip; therefore, proteins within the cells are extracted, separated from the concentrated cells and then pre-concentrated at a different location that is closer to the Nafion film. Hence, we believe that the SC-ICP devices have higher possibilities of being easily integrated with traditional microfluidic systems for analytical and biotechnological applications.

Graphical abstract: Ion concentration polarization in a single and open microchannel induced by a surface-patterned perm-selective film

Back to tab navigation

Supplementary files

Article information


Submitted
18 Sep 2012
Accepted
06 Dec 2012
First published
07 Dec 2012

Analyst, 2013,138, 1370-1378
Article type
Paper

Ion concentration polarization in a single and open microchannel induced by a surface-patterned perm-selective film

M. Kim, M. Jia and T. Kim, Analyst, 2013, 138, 1370
DOI: 10.1039/C2AN36346A

Social activity

Search articles by author

Spotlight

Advertisements