Jump to main content
Jump to site search
Access to RSC content Close the message box

Continue to access RSC content when you are not at your institution. Follow our step-by-step guide.


Issue 3, 2013
Previous Article Next Article

Coupling isotachophoresis and capillary electrophoresis: a review and comparison of methods

Author affiliations

Abstract

We present a comprehensive review and comparison of the methodologies for increasing sensitivity and resolution of capillary electrophoresis (CE) using online transient isotachophoresis (tITP). We categorize the diverse set of coupled tITP and CE (tITP-CE) methods based on their fundamental principles for disrupting isotachophoretic preconcentration and triggering electrophoretic separation. Based on this classification, we discuss important features, advantages, limitations, and optimization principles of various tITP-CE methods. We substantiate our discussion with original simulations, instructive examples, and published experimental results.

Graphical abstract: Coupling isotachophoresis and capillary electrophoresis: a review and comparison of methods

Back to tab navigation

Article information


Submitted
17 Aug 2012
Accepted
21 Nov 2012
First published
22 Nov 2012

Analyst, 2013,138, 735-754
Article type
Tutorial Review

Coupling isotachophoresis and capillary electrophoresis: a review and comparison of methods

S. S. Bahga and J. G. Santiago, Analyst, 2013, 138, 735
DOI: 10.1039/C2AN36150G

Social activity

Search articles by author

Spotlight

Advertisements