Jump to main content
Jump to site search
Access to RSC content Close the message box

Continue to access RSC content when you are not at your institution. Follow our step-by-step guide.


Issue 36, 2012
Previous Article Next Article

Conformational collapse of surface-bound helical filaments

Author affiliations

Abstract

Chiral polymers are ubiquitous in nature and in the cellular context they are often found in association with membranes. Here we show that surface bound polymers with an intrinsic twist and anisotropic bending stiffness can exhibit a sharp continuous phase transition between states with very different effective persistence lengths as the binding affinity is increased. Above a critical value of the binding strength, determined solely by the torsional modulus and intrinsic twist rate, the filament can exist in a zero twist, surface bound state with a homogeneous stiffness. Below the critical binding strength, twist walls proliferate and function as weak or floppy joints that sharply reduce the effective persistence length that is measurable on long length scales. The existence of such dramatically different conformational states has implications for both biopolymer function in vivo and for experimental observations of such filaments in vitro.

Graphical abstract: Conformational collapse of surface-bound helical filaments

Back to tab navigation

Article information


Submitted
05 Apr 2012
Accepted
21 Jun 2012
First published
17 Jul 2012

Soft Matter, 2012,8, 9460-9468
Article type
Paper

Conformational collapse of surface-bound helical filaments

D. A. Quint, A. Gopinathan and G. M. Grason, Soft Matter, 2012, 8, 9460
DOI: 10.1039/C2SM25798J

Social activity

Search articles by author

Spotlight

Advertisements