Issue 1, 2012
From the journal:

Soft Matter

Surface adsorption of fibronectin-derived peptide fragments: the influence of electrostatics and hydrophobicity for endothelial cells adhesion†

Cristina Satriano,*a   Maria Elena Fragalà,a   Giuseppe Forte,b   Anna Maria Santoro,c   Diego La Mendolac  and  Bengt Kasemod  

* Corresponding authors

a Department of Chemical Sciences and INSTM, Catania University, viale Andrea Doria, 6, Catania, Italy
E-mail: csatriano@unict.it
Fax: +39 095 580138
Tel: +39 095 7385136

b Department of Pharmaceutical Sciences, Catania University, viale Andrea Doria, 6, Catania, Italy

c Institute of Biostructures and Bioimages, CNR-Catania, viale Andrea Doria, 6, Catania, Italy

d Department of Applied Physics, Chalmers University of Technology, Gothenburg, Sweden

Abstract

The adsorption on hydrophobic and hydrophilic silica-based surfaces of the integrin-binding PHSRN peptide and the single-residual-mutated analogues, PHSEN and PHSFN, is investigated by comparative QCM-D, XPS, SFG measurements and molecular dynamics calculations. Endothelial cell cultures on the peptide-functionalized materials highlight their tunable pro- or anti-angiogenic potential.

Graphical abstract: Surface adsorption of fibronectin-derived peptide fragments: the influence of electrostatics and hydrophobicity for endothelial cells adhesion

About
Cited by
Related
Download options Please wait...

Supplementary files

Article information

DOI
https://doi.org/10.1039/C1SM06655B
Article type
Communication
Submitted
31 Aug 2011
Accepted
27 Oct 2011
First published
11 Nov 2011

Soft Matter, 2012,8, 53-56

Permissions

Request permissions

Surface adsorption of fibronectin-derived peptide fragments: the influence of electrostatics and hydrophobicity for endothelial cells adhesion

C. Satriano, M. E. Fragalà, G. Forte, A. M. Santoro, D. La Mendola and B. Kasemo, Soft Matter, 2012, 8, 53 DOI: 10.1039/C1SM06655B

To request permission to reproduce material from this article, please go to the Copyright Clearance Center request page.

If you are an author contributing to an RSC publication, you do not need to request permission provided correct acknowledgement is given.

If you are the author of this article, you do not need to request permission to reproduce figures and diagrams provided correct acknowledgement is given. If you want to reproduce the whole article in a third-party publication (excluding your thesis/dissertation for which permission is not required) please go to the Copyright Clearance Center request page.

Read more about how to correctly acknowledge RSC content.

Social activity

Spotlight

Advertisements