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In this paper, the example of noncovalently synthesized multi-compartment micelles (MCMs) has been demonstrated on the basis of a supra-amphiphilic polymer. The supra-amphiphilic polymer can be obtained directly by mixing a commercially available copolymer and a natural vitamin under weak basic conditions, further leading to the formation of MCMs.

Graphical abstract: pH and enzymatic double-stimuli responsive multi-compartment micelles from supra-amphiphilic polymers

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