Issue 29, 2012
From the journal:

Organic & Biomolecular Chemistry

Stereoselective construction of the tetracyclic core of Cryptotrione†

Song Chen,a   Chao Rong,a   Pengju Feng,a   Songlei Lia  and  Yian Shi*ab  

* Corresponding authors

a Beijing National Laboratory of Molecular Sciences, CAS Key Laboratory of Molecular Recognition and Function, Institute of Chemistry, Chinese Academy of Sciences, Beijing 100190, China

b Department of Chemistry, Colorado State University, Fort Collins, Colorado 80523, USA
E-mail: yian@lamar.colostate.edu
Fax: +(1)-970-4911801
Tel: +(1)-970-4917424

Abstract

An efficient stereoselective approach to the tetracyclic core of Cryptotrione, involving an asymmetric Michael addition, ring-closing metathesis, and subsequent cyclopropanation, is described.

Graphical abstract: Stereoselective construction of the tetracyclic core of Cryptotrione

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Article information

DOI
https://doi.org/10.1039/C2OB25923K
Article type
Communication
Submitted
14 May 2012
Accepted
14 Jun 2012
First published
14 Jun 2012

Org. Biomol. Chem., 2012,10, 5518-5520

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Stereoselective construction of the tetracyclic core of Cryptotrione

S. Chen, C. Rong, P. Feng, S. Li and Y. Shi, Org. Biomol. Chem., 2012, 10, 5518 DOI: 10.1039/C2OB25923K

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