Shaoxia Lin, Ying Wei, Fushun Liang, Baozhong Zhao, Yanling Liu and Pengjun Liu
Org. Biomol. Chem., 2012,10, 4571-4576
DOI:
10.1039/C2OB25550B,
Paper
A highly efficient multi-component anion relay cascade reaction based on 1-acetylcyclopropanecarboxamides, aldehydes and acrylonitrile has been developed, which provides strategically novel and atom-economic access to biologically important biscyanoethylated furo[3,2-c]pyridinones. In this one-pot transformation, up to five bonds (one C–N, one C–O and three C–C bonds) were constructed.
![Graphical abstract: Multi-component anion relay cascade of 1-acetylcyclopropanecarboxamides, aldehydes and acrylonitrile: access to biscyanoethylated furo[3,2-c]pyridinones](/services/images/RSCpubs.ePlatform.Service.FreeContent.ImageService.svc/ImageService/image/GA?id=C2OB25550B "Graphical abstract")
