Issue 14, 2012
From the journal:

Organic & Biomolecular Chemistry

A seminaphthofluorescein-based fluorescent chemodosimeter for the highly selective detection of cysteine†

Xiaofeng Yang,*ab   Yixing Guoa  and  Robert M. Strongin*a  

* Corresponding authors

a Department of Chemistry, Portland State University, Portland, OR 97201, USA
E-mail: Strongin@pdx.edu
Fax: +1 503-725-9525
Tel: +1 503-725-9724

b Key Laboratory of Synthetic and Natural Functional Molecule Chemistry of Ministry of Education, Institute of Analytical Sciences, College of Chemistry & Materials Science, Northwest University, Xi'an, China
E-mail: xfyang@nwu.edu.cn

Abstract

A fluorescent chemodosimeter for cysteine detection was developed based on a tandem conjugate addition and intramolecular cyclization reaction. The method exhibited an excellent selectivity for cysteine over other biothiols such as homocysteine and glutathione.

Graphical abstract: A seminaphthofluorescein-based fluorescent chemodosimeter for the highly selective detection of cysteine

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Article information

DOI
https://doi.org/10.1039/C2OB25178G
Article type
Communication
Submitted
24 Jan 2012
Accepted
22 Feb 2012
First published
24 Feb 2012

Org. Biomol. Chem., 2012,10, 2739-2741

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A seminaphthofluorescein-based fluorescent chemodosimeter for the highly selective detection of cysteine

X. Yang, Y. Guo and R. M. Strongin, Org. Biomol. Chem., 2012, 10, 2739 DOI: 10.1039/C2OB25178G

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