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Issue 30, 2012
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Water-soluble, deep-red fluorescent squaraine rotaxanes

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Abstract

Eight fluorescent squaraine rotaxanes with deep-red absorption/emission wavelengths were prepared and assessed for chemical stability and suitability as water-soluble, fluorescent tracers. The most stable squaraine rotaxanes have four large stopper groups attached to the ends of the encapsulated squaraine, and two members of this structural class have promise as highly fluorescent tracers with rapid renal clearance and very low tissue uptake in living mice.

Graphical abstract: Water-soluble, deep-red fluorescent squaraine rotaxanes

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Article information


Submitted
23 Oct 2011
Accepted
22 Nov 2011
First published
22 Nov 2011

Org. Biomol. Chem., 2012,10, 5769-5773
Article type
Communication

Water-soluble, deep-red fluorescent squaraine rotaxanes

E. L. Cole, E. Arunkumar, S. Xiao, B. A. Smith and B. D. Smith, Org. Biomol. Chem., 2012, 10, 5769
DOI: 10.1039/C2OB06783H

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