Jump to main content
Jump to site search

Issue 1, 2012
Previous Article Next Article

A concise asymmetric synthesis of (−)-rasfonin

Author affiliations


A very efficient total synthesis of the apoptosis inducer (−)-rasfonin has been developed using CuBr/JosiPhos catalyzed iterative asymmetric conjugate addition of MeMgBr and Feringa's butenolide.

Graphical abstract: A concise asymmetric synthesis of (−)-rasfonin

Back to tab navigation

Supplementary files

Publication details

The article was received on 07 Oct 2011, accepted on 25 Oct 2011 and first published on 24 Nov 2011

Article type: Communication
DOI: 10.1039/C1OB06700A
Org. Biomol. Chem., 2012,10, 29-31

  •   Request permissions

    A concise asymmetric synthesis of (−)-rasfonin

    Y. Huang, A. J. Minnaard and B. L. Feringa, Org. Biomol. Chem., 2012, 10, 29
    DOI: 10.1039/C1OB06700A

Search articles by author