Rationale for the opposite stereochemistry of the major monoadducts and interstrand crosslinks formed by mitomycin C and its decarbamoylated analogue at CpG steps in DNA and the effect of cytosine modification on reactivity†
Abstract
* Corresponding authors
a
Departamento de Farmacología, Universidad de Alcalá, E-28871 Alcalá de Henares, Madrid, Spain
E-mail:
federico.gago@uah.es
Fax: +34-918854591
Tel: +34-918854514
b Unidad de Bioinformática, Centro de Biología Molecular Severo Ochoa, 28049 Madrid, Spain
J. A. Bueren-Calabuig, A. Negri, A. Morreale and F. Gago, Org. Biomol. Chem., 2012, 10, 1543 DOI: 10.1039/C1OB06675G
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