Issue 1, 2012
From the journal:

New Journal of Chemistry

Water-soluble dendritic polyaspartic porphyrins: potential photosensitizers for photodynamic therapy†

Baoxiang Gao,*ac   Yueling Liu,a   Huijuan Yin,b   Yingxin Li,*b   Qianqian Baia  and  Licui Zhanga  

* Corresponding authors

a College of Chemistry and Environmental Science, Hebei University, Baoding, P. R. China
E-mail: bxgao@hbu.edu.cn
Fax: +86 3125079317

b Institute of Biomedical Engineering, Chinese Academy of Medical Science & Peking Union Medical College, Tianjin, P. R. China
E-mail: yingxinli@bme.org.cn
Fax: +86 22 87891131

c Key Laboratory of Medicinal Chemistry and Molecular Diagnosis, Ministry of Education, Hebei University, Baoding, P. R. China

Abstract

We prepared these photosensitizers with two-block structures: porphyrin cores for singlet oxygen generation and branched dendritic polyaspartic as hydrophilic shells for inducing water solubility, thus reducing cytotoxicity and giving high singlet oxygen yields.

Graphical abstract: Water-soluble dendritic polyaspartic porphyrins: potential photosensitizers for photodynamic therapy

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Article information

DOI
https://doi.org/10.1039/C1NJ20733D
Article type
Letter
Submitted
22 Aug 2011
Accepted
14 Oct 2011
First published
31 Oct 2011

New J. Chem., 2012,36, 28-31

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Water-soluble dendritic polyaspartic porphyrins: potential photosensitizers for photodynamic therapy

B. Gao, Y. Liu, H. Yin, Y. Li, Q. Bai and L. Zhang, New J. Chem., 2012, 36, 28 DOI: 10.1039/C1NJ20733D

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