Discovery of ferrocene-containing farnesyltransferase inhibitors. Investigation of bulky lipophilic groups for the A2 binding site of farnesyltransferase
Abstract
A new family of
* Corresponding authors
a
Univ Lille Nord de France, F-59000 Lille, France
E-mail:
benoit.rigo@hei.fr
b UCLille, EA GRIIOT (4481), Laboratoire de Pharmacochimie, HEI, 13 rue de Toul, F-59046 Lille, France
c Institut de Chimie des Substances Naturelles, UPR2301 CNRS, Centre de Recherche de Gif, Avenue de la Terrasse, F-91198 Gif-sur-Yvette Cedex, France
d Institut de Chimie Pharmaceutique Albert Lespagnol, EA4481, IFR114, 3 Rue du Pr Laguesse, B.P. 83, F-59006 Lille, France
A new family of
A. Ghinet, B. Rigo, J. Dubois, A. Farce, J. Hénichart and P. Gautret, Med. Chem. Commun., 2012, 3, 1147 DOI: 10.1039/C2MD20138K
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